What Are the Causes of Ovarian Tumors?

by Virginia Eliot

Overview

Research is ongoing into what causes ovarian tumors, with no conclusive findings. Possible causes researchers are studying include genetic mutations and changes in hormone levels during ovulation, defective genes and environmental factors.
Tissue Repair in Ovulation

Some researchers think the development of ovarian tumors may be connected to the tissue repair process during the monthly ovulation cycle. According to the Mayo Clinic, the release of an egg creates a tear in the follicle. The formation of new cells to repair the follicle leaves open the possibility for genetic mutation.

Hormonal Fluctuation

According to the Mayo Clinic, researchers are continuing to study the possibility that hormonal fluctuations throughout the ovulation cycle may cause mutant cells and lead to ovarian tumors.
Defective Genes

Women who inherit a defective form of BRAC1 and BRAC2 genes have an increased risk for certain types of ovarian tumors. The normal gene acts as a tumor suppressant; the mutation is not as effective, according to the American Cancer Society.
Environmental Factors

Although risk factors exist in the environment, the American Cancer Society states research has not yet been able to pinpoint a particular chemical or other substance as a cause of ovarian tumors.
Inherited Conditions

Women with certain inherited conditions have an increased risk of developing ovarian tumors. These conditions include Cowden's disease, Peutz-Jeghers syndrome and hereditary non-polyposis colon cancer, according to the American Cancer Society.